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This review was registered in Open Science Framework Systematic Review Registration: 1 Introduction The International Diabetes Federation (IDF) Diabetes Atlas (2025) indicates that 11.1% (or 1 in 9) of the population aged 20-79 is estimated to have diabetes, and more than 40% of that number does not have a diagnosis

Figure 2 Figure 3 Metabolites, such as phenolics, flavonoids, and tocopherols, can effectively mitigate oxidative stress and lower the risk of chronic diseases (Torres-Tiji et al., 2020)

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In contrast, FoB exhibit lower intracellular ROS and maintain a metabolic setup that is distinct from that in MZB